HIV-1-induced small T cell syncytia: susceptibility to direct NK cell killing

Abstract excerpt

Intravital imaging studies of HIV-1-infected humanized mice by three independent groups revealed the presence of small T cell syncytia. Although these multinucleated entities represent only a small fraction of infected T lymphocytes, they arise at the earliest stages of infection, are highly motile, and they make frequent contact with potential target cells. Importantly, while such transient contacts allow for vir...

Topics

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• Animal Virus Infections Studies
• Cytomegalovirus and herpesvirus research
• Herpesvirus Infections and Treatments
• HIV Research and Treatment
• Immune Cell Function and Interaction
• Parvovirus B19 Infection Studies
• Viral Infections and Immunology Research
• Virology and Viral Diseases

Identifiers and source

Literature Corpus work

ba112f51-0ab5-5ad9-af60-f2b037f0d8f3

DOI

10.64898/2026.06.14.732158