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Article

Molecular characterization of an attenuated human immunodeficiency virus type 2 isolate.

Journal of virology - 1 Feb 1990

Kumar P, Hui H X, Kappes J C, Haggarty B S, Hoxie J A, Arya S K, Shaw G M, Hahn B H

Abstract excerpt

Naturally occurring strains of human immunodeficiency virus (HIV) can vary considerably in their in vitro biological properties, and such differences may also be reflected in their in vivo pathogenesis. In an attempt to define genetic determinants of viral pathogenicity, we have molecularly cloned, sequenced, and characterized an attenuated isolate of HIV type 2 (HIV-2/ST) that differs from prototype HIV-2...

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Identifiers

PMID: 2296086
DOI: 10.1128/JVI.64.2.890-901.1990
PMCID: PMC249186

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