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Article

Molecular characterization of an attenuated human immunodeficiency virus type 2 isolate.

Journal of virology - 1 Feb 1990

Kumar P, Hui H X, Kappes J C, Haggarty B S, Hoxie J A, Arya S K, Shaw G M, Hahn B H

Abstract excerpt

Naturally occurring strains of human immunodeficiency virus (HIV) can vary considerably in their in vitro biological properties, and such differences may also be reflected in their in vivo pathogenesis. In an attempt to define genetic determinants of viral pathogenicity, we have molecularly cloned, sequenced, and characterized an attenuated isolate of HIV type 2 (HIV-2/ST) that differs from prototype HIV-2...

Topics

Amino Acid Sequence
Base Sequence
Cell Line
Cloning, Molecular
Genetic Variation
HIV-2
Humans
Molecular Sequence Data
Plasmids
Proviruses
Restriction Mapping

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Sequence Homology, Nucleic Acid

Simian Immunodeficiency Virus

T-Lymphocytes

Transfection

Source

Open in PubMed Open full text

Identifiers

PMID: 2296086
DOI: 10.1128/JVI.64.2.890-901.1990
PMCID: PMC249186

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-2296086-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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