Fusogenicity of mutant and chimeric proviruses derived from molecular clones of cytopathic and noncytopathic human immunodeficiency virus type 2.

Article

Fusogenicity of mutant and chimeric proviruses derived from molecular clones of cytopathic and noncytopathic human immunodeficiency virus type 2.

Journal of acquired immune deficiency syndromes - 1 Nov 1993

Arya S K, Sadaie M R

Abstract excerpt

Analysis of the phenotype of the molecular clones of cytopathic and fusogenic, noncytopathic and nonfusogenic, and chimeric proviruses of human immunodeficiency virus type 2 (HIV-2) suggests that the major determinant of the attenuated fusogenicity and cytopathicity of HIV-2 was located in the 3'...

Topics

Acquired Immunodeficiency Syndrome
Cloning, Molecular
Cytopathogenic Effect, Viral
Giant Cells
HIV Seropositivity
HIV-2
Humans
Mutation
Phenotype
Proviruses
Transfection

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