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Article

Clinical relevance of genetic polymorphisms in the human CYP2C subfamily.

British journal of clinical pharmacology - 1 Oct 2001

Goldstein J A

Abstract excerpt

The human CYP2Cs are an important subfamily of P450 enzymes that metabolize approximately 20% of clinically used drugs. There are four members of the subfamily, CYP2C8, CYP2C9, CYP2C19, and CYP2C18. Of these CYP2C8, CYP2C9, and CYP2C19 are of clinical importance. The CYP2Cs also metabolize some endogenous compounds such as arachidonic acid. Each member of this subfamily has been found to be genetically...

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Identifiers

PMID: 11678778
DOI: 10.1046/j.0306-5251.2001.01499.x
PMCID: PMC2014584

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Source receipt: pubmed, retrieved 7 Sept 2026.

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