Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Errors of heterologous protein expression.

Current opinion in biotechnology - 1 Oct 1996

Kurland C, Gallant J

Abstract excerpt

Missense substitutions and processivity errors in the translation of heterologous proteins are expected to occur at higher frequencies than the corresponding errors of normal translation. The resulting error-containing products may overload chaperone systems. Likewise, there may be a risk of an immunogenic response to heterologous proteins introduced into vertebrates. Recent work has been carried out on the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Biotechnology
Share to Codon
Share to Gene Expression

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Molecular Chaperones

Share to Mutation

Share to Protein Biosynthesis

Share to Recombinant Proteins

Source

Identifiers

PMID: 8939626
DOI: 10.1016/s0958-1669(96)80050-4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Errors of heterologous protein expression.PMID 8939626Read ↗

Protein mistranslation: friend or foe?Semantic proximity Read ↗

Genetic code ambiguity: an unexpected source of proteome innovation and phenotypic diversity.Semantic proximity Read ↗

Mistranslation: from adaptations to applications.Semantic proximity Read ↗

The hidden costs of imperfection: transcription errors in protein aggregation diseases.Semantic proximity Read ↗

Expression level, evolutionary rate, and the cost of expression.Semantic proximity Read ↗

Translational errors as an early event in prion conversion.Semantic proximity Read ↗

Visualizing high error levels during gene expression in living bacterial cells.Semantic proximity Read ↗

Protein mistranslation protects bacteria against oxidative stress.Semantic proximity Read ↗

Universally high transcript error rates in bacteria.Semantic proximity Read ↗

Connections between translation, transcription and replication error-rates.Semantic proximity Read ↗

Ectopic transcription: an application to the analysis of splicing errors in phenylalanine hydroxylase mRNA.Semantic proximity Read ↗

Transcriptional homeostasis: a mechanism of protein quality control.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.