Article
A comparative analysis of neuroblastic and substrate-adherent human neuroblastoma cell lines.
Journal of pediatric surgery - 1 Feb 1996
La Quaglia M P, Manchester K M
Abstract excerpt
In human neuroblastoma cell cultures, two phenotypes with differing biological properties have been described: neuroblastic (N) and substrate-adherent (Schwannian or S). In nude mice, N cells are rapidly growing, clonigenic in soft agar, and tumorigenic, whereas S cells are not. The difference in...
Topics
- Antigens, Differentiation
- Biomarkers, Tumor
- Blotting, Northern
- Cell Transformation, Neoplastic
- Gene Expression Regulation, Neoplastic
- Genes, MHC Class I
- Humans
- In Vitro Techniques
- Neuroblastoma
- Phenotype
- Tumor Cells, Cultured
- beta 2-Microglobulin