Article
Altered growth and phenotype in clonal mycN transfectants of the SK-N-SH neuroblastoma cell line.
International journal of cancer - 1 Oct 1994
Gross N, Miescher G, Beck D, Favre S, Beretta C
Abstract excerpt
We have attempted to distinguish in human neuroblastoma between the effects of mycN on differentiation and its potential to promote malignant progression. Others have observed out-growth of autocrine cells with evidence of an advanced malignant phenotype in a mycN-transfected clonal cell line derived from the single-copy mycN neuroblastoma, SK-N-SH. We have now transfected the parental cell line with the same...
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