Article
Altered growth and phenotype in clonal mycN transfectants of the SK-N-SH neuroblastoma cell line.
International journal of cancer - 1 Oct 1994
Gross N, Miescher G, Beck D, Favre S, Beretta C
Abstract excerpt
We have attempted to distinguish in human neuroblastoma between the effects of mycN on differentiation and its potential to promote malignant progression. Others have observed out-growth of autocrine cells with evidence of an advanced malignant phenotype in a mycN-transfected clonal cell line der...
Topics
- Animals
- Blotting, Northern
- Blotting, Southern
- Cell Division
- Gene Expression
- Genes, myc
- Genetic Vectors
- Histocompatibility Antigens Class I
- Kinetics
- Mice
- Mice, Nude
- Neoplasm Transplantation
- Neuroblastoma
- Phenotype
- RNA, Messenger
- S100 Proteins
- Transfection
- Tumor Cells, Cultured