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Article

Tumour-derived substrate-adherent cells promote neuroblastoma survival through secreted trophic factors.

Molecular oncology - 1 Aug 2021

Li Jing, Wang Yubing, Li Lisha, Or Penelope M-Y, Wai Wong Chi, Liu Tian, Ho Wayne L H, Chan Andrew M

Abstract excerpt

Neuroblastoma (NB) is the most common extracranial solid tumour in children. NB is highly heterogeneous and is comprised of a mixture of neuroblastic cancer cells and stromal cells. We previously reported that N-type cells (neuroblastic cells) and S-type cells (substrate-adherent cells) in the SK-N-SH cell line shared almost identical genetic backgrounds. Sublines of N- and S-type cells were isolated from an...

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Identifiers

PMID: 33932101
DOI: 10.1002/1878-0261.12969
PMCID: PMC8334291

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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