Bi-modal differentiation pattern in a new human neuroblastoma cell line in vitro.

doi:10.1002/ijc.2910510214

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Bi-modal differentiation pattern in a new human neuroblastoma cell line in vitro.

International journal of cancer - 8 May 1992

Matsushima H, Bogenmann E

Abstract excerpt

We have isolated a human neuroblastoma (NB) cell line, HTLA230, from the bone-marrow aspirate of a patient with stage-IV disease. Subcutaneous tumors after inoculation of HTLA230 cells into nude mice were composed of primitive neuroblasts which rarely contained neuro-secretory granules. Cytogenetic studies of the cell line demonstrated 2 distinct populations of cells with common chromosomal markers. Stable...

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Bi-modal differentiation pattern in a new human neuroblastoma cell line in vitro.

Abstract excerpt

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Bi-modal differentiation pattern in a new human neuroblastoma cell line in vitro.

Abstract excerpt

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