Article
Differential expression of N-myc in phenotypically distinct subclones of a human neuroblastoma cell line.
Cancer research - 1 Dec 1991
Foley J, Cohn S L, Salwen H R, Chagnovich D, Cowan J, Mason K L, Parysek L M
Abstract excerpt
Neuroblastomas are malignant childhood neoplasms that arise from derivatives of the neural crest. We report the characterization of a new neuroblastoma cell line, designated NBL-W, derived from the primary tumor of a patient with stage IVS disease (S. L. Cohn, C. V. Herst, H. S. Maurer, and S. T. Rosen, J. Clin. Oncol., 5: 1441-1444, 1987) according to the criteria of Evans [A. E. Evans, G. J. D'Angio, and J....
Topics
- Cell Differentiation
- Gene Expression Regulation, Neoplastic
- Genes, myc
- Humans
- Intermediate Filaments
- Karyotyping
- Nerve Growth Factors
- Neural Crest
- Neuroblastoma
- Phenotype
- RNA, Messenger