Article
Chromosomal integration dependent induction of junB by growth factors requires multiple flanking evolutionarily conserved sequences.
Oncogene - 7 Nov 1996
Phinney D G, Tseng S W, Hall B, Ryder K
Abstract excerpt
The junB locus contains nine flanking evolutionarily conserved sequences (FECS) that share 72% to 91% sequence identity between human and mouse. These FECS encompass the same regions of flanking DNA necessary for maximal mitogenic induction of junB. Most of the cis elements reported to date that affect junB regulation also reside within FECS. These observations suggest that the persistence of FECS through...
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