Article
Lack of association of the apoE4 allele with hippocampal sclerosis dementia.
Neuroscience letters - 2 Feb 1996
Troncoso J C, Kawas C H, Chang C K, Folstein M F, Hedreen J C
Abstract excerpt
We determined the apolipoprotein E4 (apoE) genotype in 12 cases of autopsy-confirmed hippocampal sclerosis dementia (HSD), a disorder characterized pathologically by neuronal degeneration, predominantly of temporal lobe structures, without senile plaques or neurofibrillary tangles. The frequency of the apoE4 allele in HSD was 12.5%, similar to that of a control population and significantly different from the...
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