Article
No major association of ApoE genotype with disease characteristics and MRI findings in multiple sclerosis.
Multiple sclerosis (Houndmills, Basingstoke, England) - 1 Jun 2004
Zwemmer J N P, van Veen T, van Winsen L, van Kamp G J, Barkhof F, Polman C H, Uitdehaag B M J
Abstract excerpt
BACKGROUND: Whereas a number of studies suggest that the ApoE polymorphism is not associated with disease susceptibility in multiple sclerosis (MS), results with regard to disease severity, however, are conflicting. Some studies suggest an unfavourable role of the epsilon4 allele. This study was performed to assess the association of the ApoE polymorphism with both disease susceptibility and disease course in a...
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