Apolipoprotein E epsilon 4 allele frequency is not increased in progressive supranuclear palsy.

doi:10.1212/wnl.45.9.1764

Back to search

Article

Apolipoprotein E epsilon 4 allele frequency is not increased in progressive supranuclear palsy.

Neurology - 1 Sept 1995

Tabaton M, Rolleri M, Masturzo P, Cammarata S, Angelini G, Hansen L A, Saitoh T, Petersen R B, Perry G, Richey P

Abstract excerpt

We examined apolipoprotein E (ApoE) immunoreactivity and allele frequency in 12 autopsied cases of progressive supranuclear palsy (PSP), a neurodegenerative disease characterized by diffuse neurofibrillary tangle (NFT) formation without beta-amyloid deposits. In spite of the ApoE immunoreactivity...

Topics

Alleles
Amyloid beta-Peptides
Apolipoprotein E4
Apolipoproteins E
Gene Frequency
Genotype
Humans
Immunohistochemistry
Neurofibrillary Tangles
Pons
Supranuclear Palsy, Progressive

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.