Article
The frequency of apolipoprotein E4 allele is not increased in patients with probable vascular dementia.
Acta neurologica Scandinavica - 1 May 1996
Pirttilä T, Lehtimäki T, Rinne J, Mattila K, Frey H, Nikkari T
Abstract excerpt
We used the NINDS-AIREN criteria to diagnose vascular dementia (VD), and compared apolipoprotein E (apoE) allele frequencies and apoE concentrations in serum and cerebrospinal fluid (CSF) between patients with possible (n = 19) and probable (n = 33) VD and controls (n = 105). There was no difference in apoE4 frequency between patients with probable VD and controls. Serum and CSF apoE concentrations did not differ...
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