Detection of Ki-ras and p53 gene mutations in tissue and pancreatic juice from pancreatic adenocarcinomas.

doi:10.1007/s005350050101

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Article

Detection of Ki-ras and p53 gene mutations in tissue and pancreatic juice from pancreatic adenocarcinomas.

Journal of gastroenterology - 1 Jun 1998

Kondoh S, Kaino M, Okita S, Ryozawa S, Akiyama T, Okita K

Abstract excerpt

Pancreatic carcinomas have a high incidence of Ki-ras mutations, and the genetic change is thought to occur at an early stage in the carcinogenesis. The aim of this study was to evaluate the usefulness of detecting genetic mutations in pure pancreatic juice (PPJ). DNA was extracted from tissue sp...

Topics

Aged
Autopsy
Carcinoma, Intraductal, Noninfiltrating
DNA Primers
Female
Genes, p53
Genes, ras
Humans
Male
Middle Aged
Mutation
Pancreatic Juice
Pancreatic Neoplasms
Polymerase Chain Reaction
Polymorphism, Single-Stranded Conformational

Source

Open in PubMed

Identifiers

PMID: 9658319
DOI: 10.1007/s005350050101

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-9658319-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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