Article
X-linked hypophosphatemic Gy mice: renal tubular maximum for phosphate vs. brush-border transport after low-P diet.
The American journal of physiology - 1 Feb 1994
Thornton S W, Tenenhouse H S, Martel J, Bockian R W, Meyer M H, Meyer R A
Abstract excerpt
We examined the effect of the X-linked hypophosphatemic Gy mutation on the maximal renal tubular reabsorption of phosphate (TmP) and compared the effects of phosphate deprivation on both TmP and Na(+)-dependent phosphate transport in renal brush-border membrane vesicles (BBMV). Adult female normal and Gy mice were fed a control (1.0% P) or low-phosphate (0.03% P) diet for 5 days. For TmP measurement, anesthetized...
Topics
- Absorption
- Animals
- Biological Transport
- Crosses, Genetic
- Diet
- Female
- Genotype
- Glomerular Filtration Rate
- Heterozygote
- Hypophosphatemia
- Kidney Tubules
