Article
Craniofacial abnormalities in mice with X-linked hypophosphatemic genes (Hyp or Gy).
Teratology - 1 Oct 1991
Shetty N S, Meyer R A
Abstract excerpt
X-Linked hypophosphatemia is the most common cause of metabolic rickets in humans and is characterized by a reduced renal TmP/GFR and hypophosphatemia. Clinically, these changes are associated with growth retardation including attenuated craniofacial growth, femoral and tibial bowing, and radiologic and histomorphometric evidence of rickets and osteomalacia. Similar mutations occur in mice at the Hyp and Gy gene...
Topics
- Animals
- Chromosome Mapping
- Facial Bones
- Genotype
- Hypophosphatemia, Familial
- Mice
- Mice, Inbred C57BL
- Mice, Mutant Strains
- Reference Values
- Skull
- Species Specificity
- X Chromosome