Article
Nuclear xenobiotic receptor PXR-null mouse exhibits hypophosphatemia and represses the Na/Pi-cotransporter SLC34A2.
Pharmacogenetics and genomics - 1 Jan 2010
Konno Yoshihiro, Moore Rick, Kamiya Nobuhiro, Negishi Masahiko
Abstract excerpt
OBJECTIVE: We previously found that the lack of nuclear xenobiotic receptor, PXR, decreases femoral bone mineral density (BMD) in Pxr-/- mice. Our present study aims to elucidate the inherited phenotype that correlates with the decreased BMD and to identify the PXR-regulated gene that may link wi...
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