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Article

Mesencephalic trigeminal nucleus development is dependent on Krox-20 expression.

Developmental neuroscience - 1 Jan 2000

De Shampa, Nguyen Anh Quan, Shuler Charles F, Turman Jack E

Abstract excerpt

Krox-20, a C2H2-type zinc-finger transcription factor, plays an important role in rhombomere development. This study reveals that the Krox-20 null mutation impacts the development of mesencephalic trigeminal (Me5) neurons, a cell group traditionally thought to emerge from the mesencephalon. Based on cell counting studies, we show that Krox-20 null mutants have twice as many Me5 neurons relative to wildtypes at...

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Identifiers

PMID: 15886484
DOI: 10.1159/000084532

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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