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Article

Brn3a and Islet1 act epistatically to regulate the gene expression program of sensory differentiation.

The Journal of neuroscience : the official journal of the Society for Neuroscience - 6 Jul 2011

Dykes Iain M, Tempest Lynne, Lee Su-In, Turner Eric E

Abstract excerpt

The combinatorial expression of transcription factors frequently marks cellular identity in the nervous system, yet how these factors interact to determine specific neuronal phenotypes is not well understood. Sensory neurons of the trigeminal ganglion (TG) and dorsal root ganglia (DRG) coexpress the homeodomain transcription factors Brn3a and Islet1, and past work has revealed partially overlapping programs of...

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Share to Adaptor Proteins, Signal Transducing
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Epistasis, Genetic

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Source

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Identifiers

PMID: 21734270
DOI: 10.1523/JNEUROSCI.0901-11.2011
PMCID: PMC3143040

Genes

TG

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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