Article
Allelism of PSO4 and PRP19 links pre-mRNA processing with recombination and error-prone DNA repair in Saccharomyces cerevisiae.
Nucleic acids research - 15 Oct 1996
Grey M, Düsterhöft A, Henriques J A, Brendel M
Abstract excerpt
The radiation-sensitive mutant pso4-1 of Saccharomyces cerevisiae shows a pleiotropic phenotype, including sensitivity to DNA cross-linking agents, nearly blocked sporulation and reduced mutability. We have cloned the putative yeast DNA repair gene PSO4 from a genomic library by complementation o...
Topics
- Alleles
- Cloning, Molecular
- DNA Repair
- Fungal Proteins
- Genes, Fungal
- Genetic Complementation Test
- Molecular Sequence Data
- Mutagenesis
- Mutation
- Phenotype
- RNA Processing, Post-Transcriptional
- RNA Splicing
- RNA Splicing Factors
- RNA, Messenger
- Recombination, Genetic
- Saccharomyces cerevisiae
- Saccharomyces cerevisiae Proteins
- Sequence Analysis