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Article

Allelism of PSO4 and PRP19 links pre-mRNA processing with recombination and error-prone DNA repair in Saccharomyces cerevisiae.

Nucleic acids research - 15 Oct 1996

Grey M, Düsterhöft A, Henriques J A, Brendel M

Abstract excerpt

The radiation-sensitive mutant pso4-1 of Saccharomyces cerevisiae shows a pleiotropic phenotype, including sensitivity to DNA cross-linking agents, nearly blocked sporulation and reduced mutability. We have cloned the putative yeast DNA repair gene PSO4 from a genomic library by complementation of the blocked UV-induced mutagenesis and of sporulation in diploids homozygous for pso4-1. Sequence analysis revealed...

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Identifiers

PMID: 8918805
DOI: 10.1093/nar/24.20.4009
PMCID: PMC146181

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