Article
Mutant pso8-1 of Saccharomyces cerevisiae, sensitive to photoactivated psoralens, UV radiation, and chemical mutagens, contains a rad6 missense mutant allele.
Current genetics - 1 Jul 2002
Rolla H, Grey M, Schmidt C L, Niegemann E, Brendel M, Henriques J A P
Abstract excerpt
A novel mutant isolate of Saccharomyces cerevisiae, sensitive to photoactivated mono- and bi-functional psoralens, to UV at 254 nm (UVC), and to nitrosoguanidine, was found to complement the photoactivated psoralen-sensitivity phenotype conferred by the pso1- pso7 mutations and was therefore named pso8-1. A constructed pso8-1 rad4-4 double mutant was super-sensitive to UVC, thus indicating a synergistic...
Topics
- Alleles
- Amino Acid Sequence
- Conserved Sequence
- Furocoumarins
- Genes, Fungal
- Methylnitronitrosoguanidine
- Molecular Sequence Data
- Mutagens
- Mutation, Missense
- Phenotype
- Photochemistry
- Photosensitizing Agents
- Phylogeny