Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Role of human Pso4 in mammalian DNA repair and association with terminal deoxynucleotidyl transferase

5 Sept 2003

Abstract excerpt

Terminal deoxynucleotidyl transferase (TdT; EC 2.7.7.31) adds nucleotides to DNA ends generated during V(D)J recombination that are subsequently processed by proteins involved in general double-strand break (DSB) repair pathways. We report an association between TdT and a 55-kDa protein in lymphoid cells. This protein, identified as hPso4, is a homolog of the protein encoded by the PS04/PRP19 gene in...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to DNA Repair Mechanisms
Share to Genomics and Chromatin Dynamics
Share to PARP inhibition in cancer therapy

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 12960389
DOI: 10.1073/pnas.1631060100

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Role of human Pso4 in mammalian DNA repair and association with terminal deoxynucleotidyl transferasePMID 12960389Read ↗

The Role of the Human Psoralen 4 (hPso4) Protein Complex in Replication Stress and Homologous RecombinationSemantic proximity Read ↗

Allelism of PSO4 and PRP19 links pre-mRNA processing with recombination and error-prone DNA repair in Saccharomyces cerevisiae.Semantic proximity Read ↗

Human Pot1 (Protection of Telomeres) Protein: Cytolocalization, Gene Structure, and Alternative SplicingSemantic proximity Read ↗

Localization-Dependent and -Independent Roles of SLX4 in Regulating TelomeresSemantic proximity Read ↗

Human shelterin protein POT1 prevents severe telomere instability induced by homology-directed DNA repair.Semantic proximity Read ↗

Human Telomeres Are Hypersensitive to UV-Induced DNA Damage and Refractory to RepairSemantic proximity Read ↗

Human POT1 Prevents Severe Telomere Instability Induced by Homology Directed DNA RepairSemantic proximity Read ↗

Structural and functional analysis of the human POT1-TPP1 telomeric complex.Semantic proximity Read ↗

Single strand DNA binding proteins 1 and 2 protect newly replicated telomeres.Semantic proximity Read ↗

Human POT1 protects the telomeric ds-ss DNA junction by capping the 5' end of the chromosome.Semantic proximity Read ↗

POT1b protects telomeres from end-to-end chromosomal fusions and aberrant homologous recombination.Semantic proximity Read ↗

Identification and analysis of a functional human homolog of the SPT4 gene of Saccharomyces cerevisiae.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.