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Article

A pathway for targeting soluble misfolded proteins to the yeast vacuole.

The Journal of cell biology - 1 Nov 1996

Hong E, Davidson A R, Kaiser C A

Abstract excerpt

We have evaluated the fate of misfolded protein domains in the Saccharomyces cerevisiae secretory pathway by fusing mutant forms of the NH2-terminal domain of lambda repressor protein to the secreted protein invertase. The hybrid protein carrying the wild-type repressor domain is mostly secreted to the cell surface, whereas hybrid proteins with amino acid substitutions that cause the repressor domain to be...

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Identifiers

PMID: 8909538
DOI: 10.1083/jcb.135.3.623
PMCID: PMC2121066

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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