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Article

Signal recognition particle receptor is important for cell growth and protein secretion in Saccharomyces cerevisiae.

Molecular biology of the cell - 1 Aug 1992

Ogg S C, Poritz M A, Walter P

Abstract excerpt

In mammalian cells, the signal recognition particle (SRP) receptor is required for the targeting of nascent secretory proteins to the endoplasmic reticulum (ER) membrane. We have identified the Saccharomyces cerevisiae homologue of the alpha-subunit of the SRP receptor (SR alpha) and characterized its function in vivo. S. cerevisiae SR alpha is a 69-kDa peripheral membrane protein that is 32% identical (54%...

Topics

Amino Acid Sequence
Base Sequence
Biological Transport
Cell Division
Endoplasmic Reticulum
Fungal Proteins
Gene Expression
Genes, Fungal
Membrane Proteins
Molecular Sequence Data
Mutation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Receptors, Cell Surface

Receptors, Cytoplasmic and Nuclear

Receptors, Peptide

Saccharomyces cerevisiae

Sequence Homology, Amino Acid

Source

Open in PubMed Open full text

Identifiers

PMID: 1327299
DOI: 10.1091/mbc.3.8.895
PMCID: PMC275647

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1327299-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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