Hyperproliferation of BXSB B cells is linked to the Yaa allele.

doi:10.1006/clin.1996.0170

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Article

Hyperproliferation of BXSB B cells is linked to the Yaa allele.

Clinical immunology and immunopathology - 1 Nov 1996

DesJardin L E, Butfiloski E J, Sobel E S, Schiffenbauer J

Abstract excerpt

Systemic lupus erythematosus is characterized by polyclonal B cell activation, the production of autoantibodies, and often by renal disease. Previous studies demonstrated that unfractionated B cells from several strains of mice with lupus hyperproliferate in culture when stimulated with lipopolys...

Topics

Alleles
Animals
Antibodies, Anti-Idiotypic
B-Lymphocytes
Disease Models, Animal
Genetic Linkage
Immunoglobulin M
Ionomycin
Lipopolysaccharides
Lupus Erythematosus, Systemic
Lymphocyte Activation
Male
Mice
Mice, Inbred BALB C
Mice, Inbred C57BL
Spleen
Tetradecanoylphorbol Acetate
Time Factors

Source

Open in PubMed

Identifiers

PMID: 8906745
DOI: 10.1006/clin.1996.0170

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-8906745-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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