Article
Contribution of the intracellular domain of murine Fc-gamma receptor type IIB1 to its tumor-enhancing potential.
International journal of cancer - 9 Oct 1996
Zusman T, Lisansky E, Arons E, Anavi R, Bonnerot C, Sautes C, Fridman W H, Witz I P, Ran M
Abstract excerpt
We have previously shown that Fc gamma receptor type II B1 (Fc(gamma)RIIB1), when expressed on non-lymphoid tumor cells, significantly enhanced their tumorigenic phenotype. This study elucidates the role of the intracellular domain of Fc(gamma)RIIB1 in the enhancement of the malignant phenotype o...
Topics
- 3T3 Cells
- Animals
- Antigens, CD
- Cell Line, Transformed
- Disease Progression
- Female
- Genetic Vectors
- Mice
- Mice, Inbred BALB C
- Neoplasms, Experimental
- Phenotype
- Receptors, IgG
- Transfection
- Tumor Stem Cell Assay