Article
Contribution of the intracellular domain of murine Fc-gamma receptor type IIB1 to its tumor-enhancing potential.
International journal of cancer - 9 Oct 1996
Zusman T, Lisansky E, Arons E, Anavi R, Bonnerot C, Sautes C, Fridman W H, Witz I P, Ran M
Abstract excerpt
We have previously shown that Fc gamma receptor type II B1 (Fc(gamma)RIIB1), when expressed on non-lymphoid tumor cells, significantly enhanced their tumorigenic phenotype. This study elucidates the role of the intracellular domain of Fc(gamma)RIIB1 in the enhancement of the malignant phenotype of polyoma-transformed 3T3 cells. We investigated the tumorigenic potential conferred by different variants of the...
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