Article
Tumor cells express FcgammaRI which contributes to tumor cell growth and a metastatic phenotype.
Neoplasia (New York, N.Y.) - 1 Jan 2000
Nelson M B, Nyhus J K, Oravecz-Wilson K I, Barbera-Guillem E
Abstract excerpt
High levels of circulating immune complexes containing tumor-associated antigens are associated with a poor prognosis for individuals with cancer. The ability of B cells, previously exposed to tumor-associated antigens, to promote both in vitro and in vivo tumor growth formed the rationale to evaluate the mechanism by which immune complexes may promote tumor growth. In elucidating this mechanism, FcgammaRI...
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