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Article

Overall lack of regulated secretion in a PC12 variant cell clone.

The Journal of biological chemistry - 25 Oct 1996

Corradi N, Borgonovo B, Clementi E, Bassetti M, Racchetti G, Consalez G G, Huttner W B, Meldolesi J, Rosa P

Abstract excerpt

A stable clone of PC12 neuroendocrine cells, named 27, known from previous studies to exhibit a defect of regulated secretion (lack of regulated secretory proteins, of synaptophysin, of dense granules and of catecholamine uptake and release; Clementi, E., Racchetti, G., Zacchetti, D., Panzeri, M. C., and Meldolesi, J. (1992) Eur. J. Neurosci. 4, 944-953) was characterized in detail to clarify the nature of its...

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Identifiers

PMID: 8900203
DOI: 10.1074/jbc.271.43.27116

Genes

SNAP25
VAMP2

Provenance

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