Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Dense-core granules: a specific hallmark of the neuronal/neurosecretory cell phenotype.

Journal of cell science - 15 Feb 2004

Malosio Maria Luisa, Giordano Tiziana, Laslop Andrea, Meldolesi Jacopo

Abstract excerpt

Expression of dense-core granules, a typical exocytic organelle, is widely believed to be controlled by coordinate gene expression mechanisms specific to neurones and neurosecretory cells. Recent studies in PC12 cells, however, have suggested the number of granules/cells depends on the levels of...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Chromogranin A
Share to Chromogranins
Share to Haplorhini

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Microscopy, Confocal

Share to Microscopy, Fluorescence

Share to Neurosecretory Systems

Share to PC12 Cells

Share to Secretory Vesicles

Source

Identifiers

PMID: 14734658
DOI: 10.1242/jcs.00934

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026. Prepared record publication-14734658-2026-09-01.1. Manifest publication-graph-cohort-2026-09-01.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 1 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Dense-core granules: a specific hallmark of the neuronal/neurosecretory cell phenotype.PMID 14734658Read ↗

Overall lack of regulated secretion in a PC12 variant cell clone.Semantic proximity Read ↗

Neurosecretory cells without neurosecretion: evidence of an independently regulated trait of the cell phenotype.Semantic proximity Read ↗

Establishment of variant PC12 subclones deficient in stimulation-secretion coupling.Semantic proximity Read ↗

Neurosecretion competence, an independently regulated trait of the neurosecretory cell phenotype.Semantic proximity Read ↗

Chromogranin A regulates the dynamics of neurosecretion through its interaction with phosphatidic acidSemantic proximity Read ↗

A PC12 variant lacking regulated secretory organelles: aberrant protein targeting and evidence for a factor inhibiting neuroendocrine gene expression.Semantic proximity Read ↗

Secretory granule biogenesis and neuropeptide sorting to the regulated secretory pathway in neuroendocrine cells.Semantic proximity Read ↗

Divergent functions of neuronal Rab11b in Ca2+-regulated versus constitutive exocytosis.Semantic proximity Read ↗

A role for the transcriptional repressor REST in maintaining the phenotype of neurosecretory-deficient PC12 cells.Semantic proximity Read ↗

Munc18-dependent and -independent clustering of syntaxin in the plasma membrane of cultured endocrine cells.Semantic proximity Read ↗

Neuronal peptide release is limited by secretory granule mobility.Semantic proximity Read ↗

Pantophysin is a ubiquitously expressed synaptophysin homologue and defines constitutive transport vesicles.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.