Article
Risk estimation from somatic mutation assays.
Mutation research - 1 Sept 1996
Heddle J A, Swiger R R
Abstract excerpt
The ability to quantify somatic mutations in vivo provides a new source of toxicological information that is relevant to the assessment of cancer risk. The major experimental factors that influence the mutant frequency are age, time after treatment, treatment protocol, and tissue analyzed. In unt...
Topics
- Animals
- Carcinogens
- Humans
- Mice
- Mutagenicity Tests
- Mutation
- Neoplasms
- Risk Assessment