Article
Somatic cell mutations in cancer epidemiology.
IARC scientific publications - 1 Jan 1997
Albertini R J, Hayes R B
Abstract excerpt
Somatic cell mutations arising in vivo in reporter genes and in cancer-associated genes may now be measured in humans. Background mutation levels and mutational responses following various mutagen exposures are reviewed in this chapter. The detection methods are compared for similarities and differences based on the underlying biology of the systems. Currently available data on molecular mutational spectra are...
Read the complete abstract on PubMedTopics
- Animals
- DNA Mutational Analysis
- Genes, Reporter
- Humans
- Mutagenicity Tests
- Mutation
- Neoplasms
