Article
Mutational spectra in transgenic animal research: data analysis and study design based upon the mutant or mutation frequency.
Environmental and molecular mutagenesis - 1 Jan 1996
Carr G J, Gorelick N J
Abstract excerpt
Understanding chemically induced changes in mutational spectra can aid in deciphering mechanisms of mutagenesis. In this paper, we propose the use of statistical methods that are based upon the mutation frequency, rather than simple mutant counts which have no relationship to the mutation frequen...
Topics
- Animals
- Animals, Genetically Modified
- Models, Genetic
- Models, Statistical
- Mutagenicity Tests
- Mutation
- Research Design
- Sample Size