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Article

Mice expressing mutant myosin heavy chains are a model for familial hypertrophic cardiomyopathy.

Molecular medicine (Cambridge, Mass.) - 1 Sept 1996

Vikstrom K L, Factor S M, Leinwand L A

Abstract excerpt

BACKGROUND: Familial hypertrophic cardiomyopathy (HCM) is an autosomal dominant disease characterized by ventricular hypertrophy, myocellular disarray, arrhythmias, and sudden death. Mutations in several contractile proteins, including cardiac myosin heavy chains, have been described in families with this disease, leading to the hypothesis that HCM is a disease of the sarcomere. MATERIALS AND METHODS: A mutation...

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Identifiers

PMID: 8898372
PMCID: PMC2230192

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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