Article
Role of animal models in HCM research.
Journal of cardiovascular translational research - 1 Dec 2009
Shephard Rhian, Semsarian Christopher
Abstract excerpt
Hypertrophic cardiomyopathy (HCM) is a complex cardiovascular genetic disorder characterized by marked clinical and genetic heterogeneity. Major advances have been made in the clinical characterization of patients with HCM and in identifying causative gene mutations. However, many questions remain regarding the underlying disease mechanisms. Furthermore, in a disease where no pharmacological treatments currently...
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