Article
Cytochromes P4502E1 and P4501A1 genotypes and susceptibility to cirrhosis or upper aerodigestive tract cancer in alcoholic caucasians.
Alcoholism, clinical and experimental research - 1 Sept 1996
Lucas D, Ménez C, Floch F, Gourlaouen Y, Sparfel O, Joannet I, Bodénez P, Jezequel J, Gouérou H, Berthou F, Bardou L G, Ménez J F
Abstract excerpt
Genetic polymorphisms of various cytochromes P450 have recently been described and could be implicated in the individual susceptibility of alcoholics to ethanol-related diseases. Rsal and Dral polymorphisms of CYP2E1 and Mspl polymorphism of CYP1A1 were studied in 260 controls and 511 alcoholic patients, without any clinical symptoms (n = 202) or with various ethanol-related diseases (n = 309), such as liver...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
