Cytochromes P4502E1 and P4501A1 genotypes and susceptibility to cirrhosis or upper aerodigestive tract cancer in alcoholic caucasians.

doi:10.1111/j.1530-0277.1996.tb01943.x

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Article

Cytochromes P4502E1 and P4501A1 genotypes and susceptibility to cirrhosis or upper aerodigestive tract cancer in alcoholic caucasians.

Alcoholism, clinical and experimental research - 1 Sept 1996

Lucas D, Ménez C, Floch F, Gourlaouen Y, Sparfel O, Joannet I, Bodénez P, Jezequel J, Gouérou H, Berthou F, Bardou L G, Ménez J F

Abstract excerpt

Genetic polymorphisms of various cytochromes P450 have recently been described and could be implicated in the individual susceptibility of alcoholics to ethanol-related diseases. Rsal and Dral polymorphisms of CYP2E1 and Mspl polymorphism of CYP1A1 were studied in 260 controls and 511 alcoholic p...

Topics

Adult
Alcoholism
Alleles
Cytochrome P-450 CYP1A1
Cytochrome P-450 CYP2E1
DNA Mutational Analysis
Electrophoresis, Polyacrylamide Gel
Esophageal Neoplasms
Female
Gene Frequency
Genotype
Humans
Liver Cirrhosis
Male

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Middle Aged

Otorhinolaryngologic Neoplasms

Polymerase Chain Reaction

Polymorphism, Restriction Fragment Length

Source

Open in PubMed

Identifiers

PMID: 8892524
DOI: 10.1111/j.1530-0277.1996.tb01943.x

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-8892524-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.