Roles of cytochrome P4502E1 gene polymorphisms and the risks of alcoholic liver disease: a meta-analysis.

doi:10.1371/journal.pone.0054188

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Article

Roles of cytochrome P4502E1 gene polymorphisms and the risks of alcoholic liver disease: a meta-analysis.

PloS one - 1 Jan 2013

Zeng Tao, Guo Fang-Fang, Zhang Cui-Li, Song Fu-Yong, Zhao Xiu-Lan, Xie Ke-Qin

Abstract excerpt

BACKGROUND: Previous studies investigating the association between cytochrome P4502E1 (CYP2E1) polymorphisms and the risk of alcoholic liver diseases (ALD) have yielded conflicting results. Thus, a meta-analysis was performed to clarify the association between CYP2E1 polymorphisms and the risks of ALD. METHODS: A comprehensive literature search was conducted to identify the relevant studies. The fixed or random...

Topics

Alleles
Cytochrome P-450 CYP2E1
Gene Frequency
Genetic Predisposition to Disease
Humans
Liver Diseases, Alcoholic
Polymorphism, Genetic
Population Groups
Publication Bias
Risk

Source

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Identifiers

PMID: 23335995
DOI: 10.1371/journal.pone.0054188
PMCID: PMC3545986

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