Article
Association studies of polymorphisms of CYP2E1 gene in alcoholics with cirrhosis, antisocial personality, and normal controls.
Alcoholism, clinical and experimental research - 1 Jun 1998
Parsian A, Cloninger C R, Zhang Z H
Abstract excerpt
To determine the role of CYP2E1 gene in susceptibility to alcoholism and alcohol cirrhosis, we gentoyped a sample of alcoholics with and without cirrhosis, alcoholics with antisocial personality, alcoholic families, and normal controls with RsaI, PstI, and DraI polymorphisms in the gene. Relative risk and haplotype relative risk approaches were used in genotype data analysis. The PstI polymorphism data were...
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