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Article

Regulation of human colonic cell line proliferation and phenotype by sodium butyrate.

Digestive diseases and sciences - 1 Oct 1996

Basson M D, Turowski G A, Rashid Z, Hong F, Madri J A

Abstract excerpt

Colonic butyrate may maintain mucosal differentiation and oppose carcinogenesis. We characterized butyrate effects on differentiation, proliferation, and matrix interactions in Caco-2 and SW620 human colonic cells. Differentiation was assessed by brush border enzyme activity and doubling time by serial cell counts. Motility across matrix proteins was quantitated by monolayer expansion and correlated with...

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Identifiers

PMID: 8888712
DOI: 10.1007/BF02093601

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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