Article
Regulation of human colonic cell line proliferation and phenotype by sodium butyrate.
Digestive diseases and sciences - 1 Oct 1996
Basson M D, Turowski G A, Rashid Z, Hong F, Madri J A
Abstract excerpt
Colonic butyrate may maintain mucosal differentiation and oppose carcinogenesis. We characterized butyrate effects on differentiation, proliferation, and matrix interactions in Caco-2 and SW620 human colonic cells. Differentiation was assessed by brush border enzyme activity and doubling time by...
Topics
- Butyrates
- Butyric Acid
- Cell Adhesion
- Cell Division
- Cell Line
- Cell Membrane
- Cell Movement
- Collagen
- Colon
- Dose-Response Relationship, Drug
- Fatty Acids, Volatile
- Humans
- Integrins
- Laminin
- Phenotype
- Plastics