Article
Differential modulation of human (Caco-2) colon cancer cell line phenotype by short chain fatty acids.
Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.) - 1 Apr 1998
Basson M D, Emenaker N J, Hong F
Abstract excerpt
Fermentation of dietary fiber within the colonic lumen yields short chain fatty acids (SCFA) such as butyrate, which may modulate colonic mucosal biology and inhibit the development of a malignant phenotype. However, different fibers yield varying proportions of various SCFA. We studied the effec...
Topics
- Acetates
- Alkaline Phosphatase
- Blotting, Western
- Butyrates
- Butyric Acid
- Caco-2 Cells
- Cell Division
- Cell Movement
- Fatty Acids, Volatile
- Humans
- Intestinal Mucosa
- Phenotype
- Phosphorylation
- Phosphotyrosine
- Propionates
- Proto-Oncogene Proteins c-myc