Article
Differential modulation of human (Caco-2) colon cancer cell line phenotype by short chain fatty acids.
Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.) - 1 Apr 1998
Basson M D, Emenaker N J, Hong F
Abstract excerpt
Fermentation of dietary fiber within the colonic lumen yields short chain fatty acids (SCFA) such as butyrate, which may modulate colonic mucosal biology and inhibit the development of a malignant phenotype. However, different fibers yield varying proportions of various SCFA. We studied the effects of the three most common SCFA, acetate, butyrate, and propionate, on the proliferation, adhesion, and motility of...
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