Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The effects of short-chain fatty acids on colon epithelial proliferation and survival depend on the cellular phenotype.

Journal of cancer research and clinical oncology - 1 Aug 2006

Comalada Mònica, Bailón Elvira, de Haro Oscar, Lara-Villoslada Federico, Xaus Jordi, Zarzuelo Antonio, Gálvez Julio

Abstract excerpt

PURPOSE: The short-chain fatty acids (SCFA) are produced via anaerobic bacterial fermentation of dietary fiber within the colonic lumen. Among them, butyrate is thought to protect against colon carcinogenesis. However, few studies analyze the effects of butyrate, and other SCFA, on normal epithelial cells and on epithelial regeneration during disease recovery. Since there are controversial in vitro studies, we...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Alkaline Phosphatase
Share to Butyric Acid

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Colonic Neoplasms

Share to Epithelial Cells

Share to HT29 Cells

Share to Intestinal Mucosa

Share to Proliferating Cell Nuclear Antigen

Share to Rats, Wistar

Source

Identifiers

PMID: 16788843
DOI: 10.1007/s00432-006-0092-x

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The effects of short-chain fatty acids on colon epithelial proliferation and survival depend on the cellular phenotype.PMID 16788843Read ↗

Cellular and Physiological Effects of Short-Chain Fatty AcidsSemantic proximity Read ↗

Differential modulation of human (Caco-2) colon cancer cell line phenotype by short chain fatty acids.Semantic proximity Read ↗

The effects of short-chain fatty acids on human colon cancer cell phenotype are associated with histone hyperacetylation.Semantic proximity Read ↗

Potentiation by specific short-chain fatty acids of differentiation and apoptosis in human colonic carcinoma cell lines.Semantic proximity Read ↗

Short chain fatty acids differentially modulate cellular phenotype and c-myc protein levels in primary human nonmalignant and malignant colonocytes.Semantic proximity Read ↗

Emerging role of nutritional short-chain fatty acids (SCFAs) against cancer via modulation of hematopoiesisSemantic proximity Read ↗

Does butyrate protect from colorectal cancer?Semantic proximity Read ↗

Microbiota-Derived Short-Chain Fatty Acids: New Road in Colorectal Cancer TherapySemantic proximity Read ↗

Metabolite mimicry identifies butyrate analogs with select protective functions in the intestinal mucosaSemantic proximity Read ↗

Divergent phenotypic patterns and commitment to apoptosis of Caco-2 cells during spontaneous and butyrate-induced differentiation.Semantic proximity Read ↗

Regulation of human colonic cell line proliferation and phenotype by sodium butyrate.Semantic proximity Read ↗

Butyrate as a promising therapeutic target in cancer: From pathogenesis to clinic (Review)Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.