Article
CYP2D6, N-acetylation, and xanthine oxidase activity in cystic fibrosis.
Pharmacotherapy - 1 Jan 2000
Bosso J A, Liu Q, Evans W E, Relling M V
Abstract excerpt
STUDY OBJECTIVE: To determine the activity of CYP2D6, N-acetylation, and xanthine oxidase, three drug-metabolizing enzyme systems, in patients with cystic fibrosis and compare the findings with those in individuals without the disease. DESIGN: Prospective cohort study. SETTING: General pediatrics service. PATIENTS: Fifty-nine patients with cystic fibrosis and 480 healthy Caucasian volunteers. INTERVENTIONS:...
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