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Article

Fission yeast mal2+ is required for chromosome segregation.

Molecular and cellular biology - 1 Nov 1996

Fleig U, Sen-Gupta M, Hegemann J H

Abstract excerpt

By a screen designed to isolate new fission yeast genes required for chromosome segregation, we have identified mal2+. The conditionally lethal mal2-1 allele gives rise to increased loss of a nonessential minichromosome at the permissive temperature and leads to severe missegregation of the chromosomes at the nonpermissive temperature. Cloning by complementation and subsequent sequence analysis revealed that mal2...

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Identifiers

PMID: 8887647
DOI: 10.1128/MCB.16.11.6169
PMCID: PMC231620

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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