Article
MIF2 is required for mitotic spindle integrity during anaphase spindle elongation in Saccharomyces cerevisiae.
The Journal of cell biology - 1 Oct 1993
Brown M T, Goetsch L, Hartwell L H
Abstract excerpt
The function of the essential MIF2 gene in the Saccharomyces cerevisiae cell cycle was examined by overepressing or creating a deficit of MIF2 gene product. When MIF2 was overexpressed, chromosomes missegregated during mitosis and cells accumulated in the G2 and M phases of the cell cycle. Temper...
Topics
- Alleles
- Amino Acid Sequence
- Anaphase
- Animals
- Base Sequence
- Benzimidazoles
- Blotting, Northern
- Carbamates
- Cell Cycle
- Chromosome Mapping
- Chromosomes
- Cloning, Molecular
- DNA
- DNA-Binding Proteins
- Flow Cytometry
- Fungal Proteins
- Gene Expression
- Microtubules