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Article

Positional cloning of jcpk/bpk locus of the mouse.

Mammalian genome : official journal of the International Mammalian Genome Society - 1 Apr 2003

Cogswell Cathy, Price Sarah J, Hou Xiaoying, Guay-Woodford Lisa M, Flaherty Lorraine, Bryda Elizabeth C

Abstract excerpt

By positional cloning techniques, we have identified the gene that is disrupted in the jcpk and bpk mouse models for polycystic kidney disease. This gene is the mouse homolog of the Drosophila Bicaudal C gene. Both of these mutations have been mapped to a very short stretch of Chromosome (Chr) 10. By sequencing the bicaudal C gene, Bicc1, in these models, it was found that the jcpk mutation results in a shortened...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 12682776
DOI: 10.1007/s00335-002-2241-0

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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