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Article

Genetic interaction studies link autosomal dominant and recessive polycystic kidney disease in a common pathway.

Human molecular genetics - 15 Aug 2007

Garcia-Gonzalez Miguel A, Menezes Luis F, Piontek Klaus B, Kaimori Junya, Huso David L, Watnick Terry, Onuchic Luiz F, Guay-Woodford Lisa M, Germino Gregory G

Abstract excerpt

Polycystic kidney disease (PKD) describes a heterogeneous collection of disorders that differ significantly with respect to their etiology and clinical presentation. They share, however, abnormal tubular morphology as a common feature, leading to the hypothesis that their respective gene products may function cooperatively in a common pathway to maintain tubular integrity. To study the pathobiology of one major...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 17575307
DOI: 10.1093/hmg/ddm141
PMCID: PMC2085232

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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