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Article

The lambda B cell repertoire of kappa-deficient mice.

International reviews of immunology - 1 Jan 1996

Sanchez P, Rueff-Juy D, Boudinot P, Hachemi-Rachedi S, Cazenave P A

Abstract excerpt

Analysis of the B cell repertoire is complicated by the huge diversity inherent in the germ line determined combinatory. Making use of knockout technology, kappa-deficient mice have been obtained. They constitute a shrewd model to follow the expression of an Ig minilocus, such as the lambda one,...

Topics

Animals
B-Lymphocytes
Gene Rearrangement
Immunoglobulin kappa-Chains
Immunoglobulin lambda-Chains
Mice
Mutation

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 8884431
DOI: 10.3109/08830189609061758

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-8884431-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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