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Article

The lambda B cell repertoire of kappa-deficient mice.

International reviews of immunology - 1 Jan 1996

Sanchez P, Rueff-Juy D, Boudinot P, Hachemi-Rachedi S, Cazenave P A

Abstract excerpt

Analysis of the B cell repertoire is complicated by the huge diversity inherent in the germ line determined combinatory. Making use of knockout technology, kappa-deficient mice have been obtained. They constitute a shrewd model to follow the expression of an Ig minilocus, such as the lambda one, in the normal condition compared with classical transgenic models. Indeed, in contrast to wild type mice, in which only...

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Source

Identifiers

PMID: 8884431
DOI: 10.3109/08830189609061758

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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