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The Human Cytomegalovirus Major Immediate-Early Proteins as Antagonists of Intrinsic and Innate Antiviral Host Responses

5 Nov 2009

Abstract excerpt

The major immediate-early (IE) gene of human cytomegalovirus (CMV) is believed to have a decisive role in acute infection and its activity is an important indicator of viral reactivation from latency. Although a variety of gene products are expressed from this region, the 72-kDa IE1 and the 86-kDa IE2 nuclear phosphoproteins are the most abundant and important. Both proteins have long been recognized as...

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Cytomegalovirus and herpesvirus research
Neutrophil, Myeloperoxidase and Oxidative Mechanisms
Toxoplasma gondii Research Studies

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 21994568
DOI: 10.3390/v1030760

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