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Article

Immune evasion proteins of human cytomegalovirus do not prevent a diverse CD8+ cytotoxic T-cell response in natural infection.

Blood - 15 Aug 2004

Manley Thomas J, Luy Lisa, Jones Thomas, Boeckh Michael, Mutimer Helen, Riddell Stanley R

Abstract excerpt

Although cytomegalovirus (CMV) expresses proteins that interfere with antigen presentation by class I major histocompatibility complex (MHC) molecules, CD8+ cytotoxic T cells (CTLs) are indispensable for controlling infection and maintaining latency. Here, a cytokine flow cytometry assay that employs fibroblasts infected with a mutant strain of CMV (RV798), which is deleted of the 4 viral genes that are...

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Antigen Presentation
Antigens, Viral
Cytomegalovirus
Cytomegalovirus Infections
Genes, Immediate-Early

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Histocompatibility Antigens Class I

T-Lymphocytes, Cytotoxic

Source

Identifiers

PMID: 15039282
DOI: 10.1182/blood-2003-06-1937

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

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